Ovarian Cancer Screening
Early Detection, Reassurance, and Expert Guidance
Dr. Mohamed Otify, a Consultant Gynaecologist and Gynaecological Surgeon specializing in gynaecological cancer, offers thorough evaluation and risk-based screening for ovarian cancer using modern imaging and blood-based testing.
While there is currently no national NHS screening programme for ovarian cancer, individual assessment can help detect problems early and provide peace of mind for women facing issues such as fibroids or other gynaecological concerns.
Why Early Detection Matters
Ovarian cancer is often called a “silent disease” because early stages usually cause no obvious symptoms. The ovaries sit deep within the pelvis, making changes difficult to detect through examination alone. Detecting abnormalities early can make treatment much more effective, so personalised screening and specialist follow-up are crucial—especially for women with risk factors, such as a family history of gynaecological cancer.
Screening Options
Your assessment begins with a consultation, detailed history, and pelvic examination. Screening may include one or more of the following:
1. CA125 Blood Test
A simple blood test measuring the CA125 protein, which can be raised in ovarian cancer. It can also be elevated in benign conditions such as endometriosis, fibroids, pregnancy, or menstruation, so results are always interpreted in context.
2. Pelvic Ultrasound
A transvaginal or abdominal scan examines ovarian size and structure. Abnormalities such as cysts or irregular tissue patterns may prompt further imaging or tests.
3. CT or MRI Scan
If earlier tests are abnormal, advanced imaging can provide a clearer picture and guide next steps, including laparoscopic procedures if necessary.
How Reliable Are the Tests?
CA125 and ultrasound can sometimes be abnormal even when there is no cancer (false positive) and occasionally appear normal despite cancer being present (false negative). Ongoing national studies—including the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)—have shown these tests can detect early disease, but it remains unclear whether routine screening reduces mortality overall. For high-risk women (e.g., family history or genetic predisposition), regular surveillance remains valuable alongside clinical review and patient testimonials.
Who Should Consider Screening
You may benefit from a private ovarian assessment if you:
- Have a family history of ovarian or breast cancer
- Carry a BRCA1/BRCA2 or related gene mutation
- Experience persistent bloating, abdominal swelling, or pelvic pain
- Are post-menopausal and wish to check for reassurance
Your consultant will discuss your personal risk and the most appropriate tests for you, including options for robotic surgery or hysterectomies if needed.
What to Expect
Your visit includes:
- Consultant-led consultation and pelvic examination
- CA125 blood test
- Ultrasound scan (transvaginal or abdominal)
- Same-day explanation of findings and written report
- Fast-track referral if further imaging or specialist input is required
While there is no proven national screening programme yet, individualised monitoring can provide valuable reassurance and detect abnormalities early.
To discuss ovarian screening or arrange a comprehensive gynaecological assessment, including options for an online consultation, book a private consultation with Dr. Mohamed Otify.
